Three unrelated protease inhibitors enhance accumulation of pharmaceutical recombinant proteins in Nicotiana benthamiana

Agroinfiltrated Nicotiana benthamiana is a flexible and scalable platform for recombinant protein (RP) production, but its great potential is hampered by plant proteases that degrade RPs. Here, we tested 29 candidate protease inhibitors (PIs) in agroinfiltrated N. benthamiana leaves for enhancing ac...

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Detalles Bibliográficos
Autores principales: Grosse‐Holz, Friederike, Madeira, Luisa, Zahid, Muhammad Awais, Songer, Molly, Kourelis, Jiorgos, Fesenko, Mary, Ninck, Sabrina, Kaschani, Farnusch, Kaiser, Markus, van der Hoorn, Renier A.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131417/
https://www.ncbi.nlm.nih.gov/pubmed/29509983
http://dx.doi.org/10.1111/pbi.12916

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