Multienzyme One-Pot Cascade for the Stereoselective Hydroxyethyl Functionalization of Substituted Phenols

[Image: see text] The operability and substrate scope of a redesigned vinylphenol hydratase as a single biocatalyst or as part of multienzyme cascades using either substituted coumaric acids or phenols as stable, cheap, and readily available substrates are reported.

Detalles Bibliográficos
Autores principales: Payer, Stefan E., Pollak, Hannah, Schmidbauer, Benjamin, Hamm, Florian, Juričić, Filip, Faber, Kurt, Glueck, Silvia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131518/
https://www.ncbi.nlm.nih.gov/pubmed/30110168
http://dx.doi.org/10.1021/acs.orglett.8b02058
Descripción
Sumario:[Image: see text] The operability and substrate scope of a redesigned vinylphenol hydratase as a single biocatalyst or as part of multienzyme cascades using either substituted coumaric acids or phenols as stable, cheap, and readily available substrates are reported.

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