A Type I Interferon and IL-10 Induced by Orientia tsutsugamushi Infection Suppresses Antigen-Specific T Cells and Their Memory Responses

Despite the various roles of type I interferon (type I IFN) responses during bacterial infection, its specific effects in vivo have been poorly characterized in scrub typhus caused by Orientia tsutsugamushi infection. Here, we show that type I IFNs are primarily induced via intracellular nucleic aci...

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Detalles Bibliográficos
Autores principales: Min, Chan-Ki, Kim, Hong-II, Ha, Na-Young, Kim, Yuri, Kwon, Eun-Kyung, Yen, Nguyen Thi Hai, Youn, Je-In, Jeon, Yoon Kyung, Inn, Kyung-Soo, Choi, Myung-Sik, Cho, Nam-Hyuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131522/
https://www.ncbi.nlm.nih.gov/pubmed/30233599
http://dx.doi.org/10.3389/fimmu.2018.02022

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