C-C chemokine receptor type 3 gene knockout alleviates inflammatory responses in allergic rhinitis model mice by regulating the expression of eosinophil granule proteins and immune factors

The present study aimed to investigate the effects of C-C chemokine receptor type 3 (CCR3) gene knockout on allergic rhinitis (AR) in mice, as well as the underlying molecular mechanisms. Ovalbumin was administrated to CCR3(+/+) and CCR3(−/−) BALB/c mice to establish an AR model. The mice were divid...

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Detalles Bibliográficos
Autores principales: Zhu, Xinhua, Liu, Ke, Wang, Jialin, Peng, Haisen, Pan, Qibin, Wu, Shuhong, Jiang, Yinli, Liu, Yuehui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131541/
https://www.ncbi.nlm.nih.gov/pubmed/30106146
http://dx.doi.org/10.3892/mmr.2018.9380

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