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Absence of Sirt3 aggravates cisplatin nephrotoxicity via enhanced renal tubular apoptosis and inflammation

Cisplatin-based chemotherapy is commonly used in the treatment of solid tumors; however, this agent is limited by its adverse effects on normal tissues, including the kidneys, ears and peripheral nerves. Mechanisms of cisplatin nephrotoxicity are proposed to involve oxidative stress, inflammation, c...

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Detalles Bibliográficos
Autores principales:	Kim, Dal, Park, Woong, Lee, Sik, Kim, Won, Park, Sung Kwang, Kang, Kyung Pyo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131565/ https://www.ncbi.nlm.nih.gov/pubmed/30106119 http://dx.doi.org/10.3892/mmr.2018.9350

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