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Studying Huntington’s Disease in Yeast: From Mechanisms to Pharmacological Approaches

Huntington’s disease (HD) is a neurodegenerative disorder that leads to progressive neuronal loss, provoking impaired motor control, cognitive decline, and dementia. So far, HD remains incurable, and available drugs are effective only for symptomatic management. HD is caused by a mutant form of the...

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Detalles Bibliográficos
Autores principales: Hofer, Sebastian, Kainz, Katharina, Zimmermann, Andreas, Bauer, Maria A., Pendl, Tobias, Poglitsch, Michael, Madeo, Frank, Carmona-Gutierrez, Didac
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131589/
https://www.ncbi.nlm.nih.gov/pubmed/30233317
http://dx.doi.org/10.3389/fnmol.2018.00318