Cargando…

Studying Huntington’s Disease in Yeast: From Mechanisms to Pharmacological Approaches

Huntington’s disease (HD) is a neurodegenerative disorder that leads to progressive neuronal loss, provoking impaired motor control, cognitive decline, and dementia. So far, HD remains incurable, and available drugs are effective only for symptomatic management. HD is caused by a mutant form of the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hofer, Sebastian, Kainz, Katharina, Zimmermann, Andreas, Bauer, Maria A., Pendl, Tobias, Poglitsch, Michael, Madeo, Frank, Carmona-Gutierrez, Didac
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131589/ https://www.ncbi.nlm.nih.gov/pubmed/30233317 http://dx.doi.org/10.3389/fnmol.2018.00318

Ejemplares similares

Yeast as a tool to identify anti-aging compounds
por: Zimmermann, Andreas, et al.
Publicado: (2018)

Autophagy: one more Nobel Prize for yeast
por: Zimmermann, Andreas, et al.
Publicado: (2016)

Digesting the crisis: autophagy and coronaviruses
por: Carmona-Gutierrez, Didac, et al.
Publicado: (2020)

Cell Stress - a new journal for cellular pathophysiology
por: Zimmermann, Andreas, et al.
Publicado: (2017)

A hundred spotlights on microbiology: how microorganisms shape our lives
por: Carmona-Gutierrez, Didac, et al.
Publicado: (2022)

Microbial wars: Competition in ecological niches and within the microbiome
por: Bauer, Maria A., et al.
Publicado: (2018)

Fungal infections in humans: the silent crisis
por: Kainz, Katharina, et al.
Publicado: (2020)

Sexually transmitted infections: old foes on the rise
por: Carmona-Gutierrez, Didac, et al.
Publicado: (2016)

Murals meet microbes: at the crossroads of microbiology and cultural heritage
por: Bauer, Maria A., et al.
Publicado: (2021)

Metabolites in aging and autophagy
por: Schroeder, Sabrina, et al.
Publicado: (2014)

The rise of Candida auris: from unique traits to co-infection potential
por: Egger, Nadine B., et al.
Publicado: (2022)

The sweet taste of death: glucose triggers apoptosis during yeast chronological aging
por: Ruckenstuhl, Christoph, et al.
Publicado: (2010)

4,4'Dimethoxychalcone: a natural flavonoid that promotes health through autophagy-dependent and -independent effects
por: Zimmermann, Andreas, et al.
Publicado: (2019)

Targeting GATA transcription factors – a novel strategy for anti-aging interventions?
por: Zimmermann, Andreas, et al.
Publicado: (2019)

Spermidine supplementation in rare translation-associated disorders
por: Zimmermann, Andreas, et al.
Publicado: (2021)

The metabolism beyond programmed cell death in yeast
por: Ring, Julia, et al.
Publicado: (2012)

When less is more: hormesis against stress and disease
por: Zimmermann, Andreas, et al.
Publicado: (2014)

Why yeast cells can undergo apoptosis: death in times of peace, love, and war
por: Büttner, Sabrina, et al.
Publicado: (2006)

The ups and downs of caloric restriction and fasting: from molecular effects to clinical application
por: Hofer, Sebastian J, et al.
Publicado: (2021)

The cell death protease Kex1p is essential for hypochlorite-induced apoptosis in yeast
por: Carmona-Gutierrez, Didac, et al.
Publicado: (2013)

The Warburg Effect Suppresses Oxidative Stress Induced Apoptosis in a Yeast Model for Cancer
por: Ruckenstuhl, Christoph, et al.
Publicado: (2009)

Spermidine: a physiological autophagy inducer acting as an anti-aging vitamin in humans?
por: Madeo, Frank, et al.
Publicado: (2018)

Acetyl-coenzyme A: A metabolic master regulator of autophagy and longevity
por: Schroeder, Sabrina, et al.
Publicado: (2014)

Polyamines in aging and disease
por: Minois, Nadège, et al.
Publicado: (2011)

One cell, one love: a journal for microbial research
por: Carmona-Gutierrez, Didac, et al.
Publicado: (2014)

3,4‐Dimethoxychalcone induces autophagy through activation of the transcription factors TFE3 and TFEB
por: Chen, Guo, et al.
Publicado: (2019)

A histone point mutation that switches on autophagy
por: Eisenberg, Tobias, et al.
Publicado: (2014)

Neurotoxic 43-kDa TAR DNA-binding Protein (TDP-43) Triggers Mitochondrion-dependent Programmed Cell Death in Yeast
por: Braun, Ralf J., et al.
Publicado: (2011)

The neuroprotective steroid progesterone promotes mitochondrial uncoupling, reduces cytosolic calcium and augments stress resistance in yeast cells
por: Stekovic, Slaven, et al.
Publicado: (2017)

Spermidine delays aging in humans
por: Madeo, Frank, et al.
Publicado: (2018)

The many ways to age for a single yeast cell
por: Carmona-Gutierrez, Didac, et al.
Publicado: (2014)

Molecular targets of spermidine: implications for cancer suppression
por: Zimmermann, Andreas, et al.
Publicado: (2023)

Targeting the autophagy-lysosomal pathway in Huntington disease: a pharmacological perspective
por: Yang, Junsheng, et al.
Publicado: (2023)

Ethanolamine: A novel anti-aging agent
por: Rockenfeller, Patrick, et al.
Publicado: (2015)

The Coordinated Action of Calcineurin and Cathepsin D Protects Against α-Synuclein Toxicity
por: Aufschnaiter, Andreas, et al.
Publicado: (2017)

Current Pharmacological Approaches to Reduce Chorea in Huntington’s Disease
por: Coppen, Emma M., et al.
Publicado: (2016)

Diacylglycerol triggers Rim101 pathway–dependent necrosis in yeast: a model for lipotoxicity
por: Rockenfeller, Patrick, et al.
Publicado: (2017)

Commentary: Acanthocytes identified in Huntington's disease
por: Peikert, Kevin, et al.
Publicado: (2022)

Pain in Huntington’s disease and its potential mechanisms
por: Li, Jiajie, et al.
Publicado: (2023)

The flavonoid 4,4′-dimethoxychalcone promotes autophagy-dependent longevity across species
por: Carmona-Gutierrez, Didac, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_qnv2jooqvjrvf9taa804g5vonp