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The Fluorescent D-Amino Acid NADA as a Tool to Study the Conditional Activity of Transpeptidases in Escherichia coli
The enzymes responsible for the synthesis of the peptidoglycan (PG) layer constitute a fundamental target for a large group of antibiotics. The family of β-lactam antibiotics inhibits the DD-transpeptidase (TPase) activity of the penicillin binding proteins (PBPs), whereas its subgroup of carbapenem...
Autores principales: | Montón Silva, Alejandro, Otten, Christian, Biboy, Jacob, Breukink, Eefjan, VanNieuwenhze, Michael, Vollmer, Waldemar, den Blaauwen, Tanneke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131605/ https://www.ncbi.nlm.nih.gov/pubmed/30233559 http://dx.doi.org/10.3389/fmicb.2018.02101 |
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