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RXFP1 Receptor Activation by Relaxin-2 Induces Vascular Relaxation in Mice via a Gα(i2)-Protein/PI3Kß/γ/Nitric Oxide-Coupled Pathway

Background: Relaxins are small peptide hormones, which are novel candidate molecules that play important roles in cardiometablic syndrome. Relaxins are structurally related to the insulin hormone superfamily, which provide vasodilatory effects by activation of G-protein-coupled relaxin receptors (RX...

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Detalles Bibliográficos
Autores principales: Lian, Xiaoming, Beer-Hammer, Sandra, König, Gabriele M., Kostenis, Evi, Nürnberg, Bernd, Gollasch, Maik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131674/
https://www.ncbi.nlm.nih.gov/pubmed/30233409
http://dx.doi.org/10.3389/fphys.2018.01234