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RXFP1 Receptor Activation by Relaxin-2 Induces Vascular Relaxation in Mice via a Gα(i2)-Protein/PI3Kß/γ/Nitric Oxide-Coupled Pathway
Background: Relaxins are small peptide hormones, which are novel candidate molecules that play important roles in cardiometablic syndrome. Relaxins are structurally related to the insulin hormone superfamily, which provide vasodilatory effects by activation of G-protein-coupled relaxin receptors (RX...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131674/ https://www.ncbi.nlm.nih.gov/pubmed/30233409 http://dx.doi.org/10.3389/fphys.2018.01234 |