Cargando…

4-Phenyl-1,3-thiazole-2-amines as scaffolds for new antileishmanial agents

BACKGROUND: There is still a need for new alternatives in pharmacological therapy for neglected diseases, as the drugs available show high toxicity and parenteral administration. That is the case for the treatment of leishmaniasis, particularly to the cutaneous clinical form of the disease. In this...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rodrigues, Carina Agostinho, dos Santos, Paloma Freire, da Costa, Marcela Oliveira Legramanti, Pavani, Thais Fernanda Amorim, Xander, Patrícia, Geraldo, Mariana Marques, Mengarda, Ana, de Moraes, Josué, Rando, Daniela Gonçales Galasse
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131760/ https://www.ncbi.nlm.nih.gov/pubmed/30214457 http://dx.doi.org/10.1186/s40409-018-0163-x

Ejemplares similares

A QSAR Study for Antileishmanial 2-Phenyl-2,3-dihydrobenzofurans †
por: Bernal, Freddy A., et al.
Publicado: (2023)

2-Bromo-4-phenyl-1,3-thiazole
por: Bunev, Alexander S., et al.
Publicado: (2014)

Targeting the Schistosoma mansoni nutritional mechanisms to design new antischistosomal compounds
por: Pavani, Thaís F. A., et al.
Publicado: (2023)

Synthesis and Antibacterial Assessment of N-[4-(4-substituted phenyl)-1,3-thiazol-2-yl]-1,3,5-triazin-2-amine
por: Gahtori, P., et al.
Publicado: (2009)

Phenyl N-(1,3-thiazol-2-yl)carbamate
por: Tang, Jian-Guo, et al.
Publicado: (2009)

The Existing Drug Nifuroxazide as an Antischistosomal Agent: In Vitro, In Vivo, and In Silico Studies of Macromolecular Targets
por: Roquini, Vinícius, et al.
Publicado: (2023)

Antileishmanial Activity of Handroanthus serratifolius (Vahl) S. Grose (Bignoniaceae)
por: Costa, Erica Vanessa Souza, et al.
Publicado: (2017)

Efficient Dimerization Disruption of Leishmania infantum Trypanothione Reductase by Triazole-phenyl-thiazoles
por: Revuelto, Alejandro, et al.
Publicado: (2021)

N-(2,4-Dichlorophenyl)-1,3-thiazol-2-amine
por: Babar, Ayesha, et al.
Publicado: (2012)

The Design, Synthesis and Evaluation of Rho-kinase Inhibitory Activity of 4-aryl-thiazole-2-amines
por: Wang, Linan, et al.
Publicado: (2021)

5-Bromo-4-(3,4-dimethoxyphenyl)thiazol-2-amine
por: Ghabbour, Hazem A., et al.
Publicado: (2012)

N-(2,4,6-Trimethylphenyl)-1,3-thiazol-2-amine
por: Babar, Ayesha, et al.
Publicado: (2012)

4-(2,4,6-Trimethylbenzyl)-1,3-thiazol-2-amine
por: Maharramov, Abel M., et al.
Publicado: (2011)

Hypervalent iodine-promoted twofold oxidative coupling of amines with amides and thioamides: chemoselective pathway to oxazoles and thiazoles
por: Nan, Jiang, et al.
Publicado: (2023)

Evaluation of Safety and Antileishmanial Efficacy of Amine Functionalized Carbon-Based Composite Nanoparticle Appended With Amphotericin B: An in vitro and Preclinical Study
por: Gedda, Mallikarjuna Rao, et al.
Publicado: (2020)

Developments in Diagnosis and Antileishmanial Drugs
por: Bhargava, Prachi, et al.
Publicado: (2012)

4-(Indol-3-yl)thiazole-2-amines and 4-ιndol-3-yl)thiazole Acylamines as Νovel Antimicrobial Agents: Synthesis, In Silico and In Vitro Evaluation
por: Simakov, Sergei, et al.
Publicado: (2021)

Cytotoxic and Antileishmanial Effects of the Monoterpene β-Ocimene
por: de Sousa, Julyanne Maria Saraiva, et al.
Publicado: (2023)

Virtual Screening and the In Vitro Assessment of the Antileishmanial Activity of Lignans
por: dos Santos Maia, Mayara, et al.
Publicado: (2020)

4-Methyl-6-phenylpyrimidin-2-amine
por: Li, Zhen-Jiang, et al.
Publicado: (2008)

Ethyl 2-phenyl-5-trifluoromethyl-1,3-thiazole-4-carboxylate
por: Jiang, Hai-Zhen, et al.
Publicado: (2008)

Antileishmanial Metabolites from Geosmithia langdonii
por: Malak, Lourin G., et al.
Publicado: (2014)

Strategies to Overcome Antileishmanial Drugs Unresponsiveness
por: Sundar, Shyam, et al.
Publicado: (2014)

Brazilian Propolis Antileishmanial and Immunomodulatory Effects
por: da Silva, Suelen Santos, et al.
Publicado: (2013)

Design and Synthesis of Novel Antileishmanial Compounds
por: Loedige, Melanie
Publicado: (2015)

Antileishmanial activity of 5-nitroindazole derivatives
por: Mollineda-Diogo, Niurka, et al.
Publicado: (2023)

4-(4-Bromophenyl)-thiazol-2-amine derivatives: synthesis, biological activity and molecular docking study with ADME profile
por: Sharma, Deepika, et al.
Publicado: (2019)

Synthesis and bioevaluation of N,4-diaryl-1,3-thiazole-2-amines as tubulin inhibitors with potent antiproliferative activity
por: Sun, Maolin, et al.
Publicado: (2017)

Antileishmanial Activity of Medicinal Plants Used in Endemic Areas in Northeastern Brazil
por: De Queiroz, Aline Cavalcanti, et al.
Publicado: (2014)

Crystal structures of ethyl {2-[4-(4-isopropylphenyl)thiazol-2-yl]phenyl}carbamate and ethyl {2-[4-(3-nitrophenyl)thiazol-2-yl]phenyl}carbamate
por: Sukhonosova, Elena V., et al.
Publicado: (2016)

(E)-Benzyl(1-phenylethylidene)amine
por: Majer, Sean H., et al.
Publicado: (2013)

5-Phenyl-1,3,4-oxadiazol-2-amine
por: Song, Man-Man, et al.
Publicado: (2012)

1-(5-Bromo-4-phenyl-1,3-thiazol-2-yl)pyrrolidin-2-one
por: Ghabbour, Hazem A., et al.
Publicado: (2012)

(E)-Methyl 1,3-thiazol-2-yl ketone 2,4-dinitrophenylhydrazone
por: Shan, Shang, et al.
Publicado: (2008)

Synthesis and Biological Activity of 3-[Phenyl(1,3-thiazol-2-yl)-amino]propanoic Acids and Their Derivatives
por: Mickevičius, Vytautas, et al.
Publicado: (2013)

2-[3-(4-Bromophenyl)-5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-1-yl]-4-phenyl-1,3-thiazole
por: Abdel-Wahab, Bakr F., et al.
Publicado: (2013)

Potential Antileishmanial Effect of Three Medicinal Plants
por: Eltayeb, A., et al.
Publicado: (2012)

The Antiacetylcholinesterase and Antileishmanial Activities of Canarium patentinervium Miq.
por: Mogana, R., et al.
Publicado: (2014)

Antileishmanial Activity of the Estrogen Receptor Modulator Raloxifene
por: Reimão, Juliana Q., et al.
Publicado: (2014)

Antileishmanial activity of diterpene acids in copaiba oil
por: dos Santos, Adriana Oliveira, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_cts8vtqcc1950mnqv7f6kj5h5f