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Pluronic-based nano-self-assemblies of bacitracin A with a new mechanism of action for an efficient in vivo therapeutic effect against bacterial peritonitis
BACKGROUND: Although assemblies of hydrophobic-modified bacitracin A with PLGA (Nano-BA(PLGA)) have demonstrated promising antibacterial activities against both Gram-positive and Gram-negative bacteria, the desirable antibacterial potency has remained challenging due to the low solubility of Nano-BA...
Autores principales: | Hong, Wei, Liu, Lipeng, Zhao, Yining, Liu, Yinghui, Zhang, Dexian, Liu, Mingchun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131780/ https://www.ncbi.nlm.nih.gov/pubmed/30205822 http://dx.doi.org/10.1186/s12951-018-0397-3 |
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