A novel synthetic trivalent single chain variable fragment (tri-scFv) construction platform based on the SpyTag/SpyCatcher protein ligase system

BACKGROUND: Advances in antibody engineering provide strategies to construct recombinant antibody-like molecules with modified pharmacokinetic properties. Multermerization is one strategy that has been used to produce antibody-like molecules with two or more antigen binding sites. Multimerization en...

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Detalles Bibliográficos
Autores principales: Alam, Md. Kausar, Brabant, Michelle, Viswas, Raja Solomon, Barreto, Kris, Fonge, Humphrey, Ronald Geyer, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131909/
https://www.ncbi.nlm.nih.gov/pubmed/30200951
http://dx.doi.org/10.1186/s12896-018-0466-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131909/
https://www.ncbi.nlm.nih.gov/pubmed/30200951
http://dx.doi.org/10.1186/s12896-018-0466-6

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