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Inhibition of HIF-1α Reduced Blood Brain Barrier Damage by Regulating MMP-2 and VEGF During Acute Cerebral Ischemia

Increase of blood brain barrier (BBB) permeability after acute ischemia stroke is a predictor to intracerebral hemorrhage transformation (HT) for tissue plasminogen activator (tPA) thrombolysis and post-endovascular treatment. Previous studies showed that 2-h ischemia induced damage of BBB integrity...

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Detalles Bibliográficos
Autores principales:	Shen, Yufei, Gu, Jingxia, Liu, Ziyun, Xu, Congying, Qian, Shuxia, Zhang, Xiaoling, Zhou, Beiqun, Guan, Qiaobing, Sun, Yanyun, Wang, Yanping, Jin, Xinchun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132021/ https://www.ncbi.nlm.nih.gov/pubmed/30233326 http://dx.doi.org/10.3389/fncel.2018.00288

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