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Quality Over Quantity: Advantages of Using Alpha-Synuclein Preformed Fibril Triggered Synucleinopathy to Model Idiopathic Parkinson’s Disease

Animal models have significantly advanced our understanding of Parkinson’s disease (PD). Alpha-synuclein (α-syn) has taken center stage due to its genetic connection to familial PD and localization to Lewy bodies, one pathological hallmark of PD. Animal models developed on the premise of elevated al...

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Detalles Bibliográficos
Autores principales:	Duffy, Megan F., Collier, Timothy J., Patterson, Joseph R., Kemp, Christopher J., Fischer, D. Luke, Stoll, Anna C., Sortwell, Caryl E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132025/ https://www.ncbi.nlm.nih.gov/pubmed/30233303 http://dx.doi.org/10.3389/fnins.2018.00621

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