Cargando…

Structural principles of distinct assemblies of the human α4β2 nicotinic receptor

Fast chemical communication in the nervous system is mediated by neurotransmitter-gated ion channels. The prototypical member of this class of cell surface receptors is the cation-selective nicotinic acetylcholine receptor. As with most ligand-gated ion channels, nicotinic receptors assemble as olig...

Descripción completa

Detalles Bibliográficos
Autores principales: Walsh, Richard M., Roh, Soung-Hun, Gharpure, Anant, Morales-Perez, Claudio L., Teng, Jinfeng, Hibbs, Ryan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132059/
https://www.ncbi.nlm.nih.gov/pubmed/29720657
http://dx.doi.org/10.1038/s41586-018-0081-7