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Bilateral Hip Fracture in Adolescents With Antiretroviral Treatment
Tenofovir is a nucleotide reverse transcriptase inhibitor, a commonly prescribed antiretroviral as part of initial therapy. It is widely used and has been recognized as a cause of acquired Fanconi syndrome, a disorder characterized by renal tubular dysfunction, which leads to hypophosphatemia, hypok...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132306/ https://www.ncbi.nlm.nih.gov/pubmed/30211347 http://dx.doi.org/10.5435/JAAOSGlobal-D-17-00005 |
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author | Marco, Poblete Cristian, Artigas Isabel, Galaz Maria Veronica, Vilches Juan, Hernandez |
author_facet | Marco, Poblete Cristian, Artigas Isabel, Galaz Maria Veronica, Vilches Juan, Hernandez |
author_sort | Marco, Poblete |
collection | PubMed |
description | Tenofovir is a nucleotide reverse transcriptase inhibitor, a commonly prescribed antiretroviral as part of initial therapy. It is widely used and has been recognized as a cause of acquired Fanconi syndrome, a disorder characterized by renal tubular dysfunction, which leads to hypophosphatemia, hypokalemia, and metabolic acidosis, as well as symptoms of polyuria and dehydration, which can ultimately lead to defects in bone mineralization and increase risk of fracture. |
format | Online Article Text |
id | pubmed-6132306 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Wolters Kluwer |
record_format | MEDLINE/PubMed |
spelling | pubmed-61323062018-09-12 Bilateral Hip Fracture in Adolescents With Antiretroviral Treatment Marco, Poblete Cristian, Artigas Isabel, Galaz Maria Veronica, Vilches Juan, Hernandez J Am Acad Orthop Surg Glob Res Rev Case Reports Tenofovir is a nucleotide reverse transcriptase inhibitor, a commonly prescribed antiretroviral as part of initial therapy. It is widely used and has been recognized as a cause of acquired Fanconi syndrome, a disorder characterized by renal tubular dysfunction, which leads to hypophosphatemia, hypokalemia, and metabolic acidosis, as well as symptoms of polyuria and dehydration, which can ultimately lead to defects in bone mineralization and increase risk of fracture. Wolters Kluwer 2017-03-31 /pmc/articles/PMC6132306/ /pubmed/30211347 http://dx.doi.org/10.5435/JAAOSGlobal-D-17-00005 Text en Copyright © 2017 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of the American Academy of Orthopaedic Surgeons This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. |
spellingShingle | Case Reports Marco, Poblete Cristian, Artigas Isabel, Galaz Maria Veronica, Vilches Juan, Hernandez Bilateral Hip Fracture in Adolescents With Antiretroviral Treatment |
title | Bilateral Hip Fracture in Adolescents With Antiretroviral Treatment |
title_full | Bilateral Hip Fracture in Adolescents With Antiretroviral Treatment |
title_fullStr | Bilateral Hip Fracture in Adolescents With Antiretroviral Treatment |
title_full_unstemmed | Bilateral Hip Fracture in Adolescents With Antiretroviral Treatment |
title_short | Bilateral Hip Fracture in Adolescents With Antiretroviral Treatment |
title_sort | bilateral hip fracture in adolescents with antiretroviral treatment |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132306/ https://www.ncbi.nlm.nih.gov/pubmed/30211347 http://dx.doi.org/10.5435/JAAOSGlobal-D-17-00005 |
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