Cargando…
Anisomycin Activates Utrophin Upregulation Through a p38 Signaling Pathway
Duchenne muscular dystrophy is a recessive X‐linked disease characterized by progressive muscle wasting; cardiac or respiratory failure causes death in most patients by the third decade. The disease is caused by mutations in the dystrophin gene that lead to a loss of functional dystrophin protein....
Autores principales: | Hadwen, Jeremiah, Farooq, Faraz, Witherspoon, Luke, Schock, Sarah, Mongeon, Kevin, MacKenzie, Alex |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132359/ https://www.ncbi.nlm.nih.gov/pubmed/29877606 http://dx.doi.org/10.1111/cts.12562 |
Ejemplares similares
-
VPAC2 receptor agonist BAY 55-9837 increases SMN protein levels and moderates disease phenotype in severe spinal muscular atrophy mouse models
por: Hadwen, Jeremiah, et al.
Publicado: (2014) -
Separating the Wheat from the Chaff: The Use of Upstream Regulator Analysis to Identify True Differential Expression of Single Genes within Transcriptomic Datasets
por: Hadwen, Jeremiah, et al.
Publicado: (2021) -
Modulation of the p38 MAPK Pathway by Anisomycin Promotes Ferroptosis of Hepatocellular Carcinoma through Phosphorylation of H3S10
por: Chen, Wei, et al.
Publicado: (2022) -
Mining the transcriptome for rare disease therapies: a comparison of the efficiencies of two data mining approaches and a targeted cell-based drug screen
por: Mears, A. J., et al.
Publicado: (2017) -
Current and emerging treatment options for spinal muscular atrophy
por: Farooq, Faraz, et al.
Publicado: (2015)