Population Pharmacokinetic and Exposure–dizziness Modeling for a Metabotropic Glutamate Receptor Subtype 5 Negative Allosteric Modulator in Major Depressive Disorder Patients

Dizziness, the most frequently observed adverse event in patients with major depressive disorder, was observed with basimglurant, a selective, orally active metabotropic glutamate receptor subtype 5 negative allosteric modulator. The potential relationship between dizziness and basimglurant exposure...

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Detalles Bibliográficos
Autores principales: Cosson, Valérie, Schaedeli‐Stark, Franziska, Arab‐Alameddine, Mona, Chavanne, Clarisse, Guerini, Elena, Derks, Michael, Mallalieu, Navita L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132363/
https://www.ncbi.nlm.nih.gov/pubmed/29877614
http://dx.doi.org/10.1111/cts.12566

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