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Senomic view of the cell: Senome versus Genome

In the legacy of Thomas Henry Huxley, and his ‘epigenetic’ philosophy of biology, cells are proposed to represent a trinity of three memory-storing media: Senome, Epigenome, and Genome that together comprise a cell-wide informational architecture. Our current preferential focus on the Genome needs t...

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Detalles Bibliográficos
Autores principales: Baluška, František, Miller, Jr, William B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132427/
https://www.ncbi.nlm.nih.gov/pubmed/30214674
http://dx.doi.org/10.1080/19420889.2018.1489184
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author Baluška, František
Miller, Jr, William B.
author_facet Baluška, František
Miller, Jr, William B.
author_sort Baluška, František
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description In the legacy of Thomas Henry Huxley, and his ‘epigenetic’ philosophy of biology, cells are proposed to represent a trinity of three memory-storing media: Senome, Epigenome, and Genome that together comprise a cell-wide informational architecture. Our current preferential focus on the Genome needs to be complemented by a similar focus on the Epigenome and a here proposed Senome, representing the sum of all the sensory experiences of the cognitive cell and its sensing apparatus. Only then will biology be in a position to embrace the whole complexity of the eukaryotic cell, understanding its true nature which allows the communicative assembly of cells in the form of sentient multicellular organisms.
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spelling pubmed-61324272018-09-13 Senomic view of the cell: Senome versus Genome Baluška, František Miller, Jr, William B. Commun Integr Biol Review In the legacy of Thomas Henry Huxley, and his ‘epigenetic’ philosophy of biology, cells are proposed to represent a trinity of three memory-storing media: Senome, Epigenome, and Genome that together comprise a cell-wide informational architecture. Our current preferential focus on the Genome needs to be complemented by a similar focus on the Epigenome and a here proposed Senome, representing the sum of all the sensory experiences of the cognitive cell and its sensing apparatus. Only then will biology be in a position to embrace the whole complexity of the eukaryotic cell, understanding its true nature which allows the communicative assembly of cells in the form of sentient multicellular organisms. Taylor & Francis 2018-08-10 /pmc/articles/PMC6132427/ /pubmed/30214674 http://dx.doi.org/10.1080/19420889.2018.1489184 Text en © 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Baluška, František
Miller, Jr, William B.
Senomic view of the cell: Senome versus Genome
title Senomic view of the cell: Senome versus Genome
title_full Senomic view of the cell: Senome versus Genome
title_fullStr Senomic view of the cell: Senome versus Genome
title_full_unstemmed Senomic view of the cell: Senome versus Genome
title_short Senomic view of the cell: Senome versus Genome
title_sort senomic view of the cell: senome versus genome
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132427/
https://www.ncbi.nlm.nih.gov/pubmed/30214674
http://dx.doi.org/10.1080/19420889.2018.1489184
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