Are laboratory parameter (biomarker) values similar to the healthy volunteer reference range in all patient populations?

BACKGROUND: Liver biomarkers alanine aminotransferase (ALT) and bilirubin in patients with hepatitis are above the healthy volunteer reference range (HVRR) at baseline (prior to receiving the clinical trial medication). Discussions continue as how to best distinguish drug-induced liver injury in pat...

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Detalles Bibliográficos
Autores principales: Brott, David A, Goodman, Michael J, Hermann, Richard P, Merz, Michael, Calvo, Roser, Poorkhalkali, Nadereh, Kiazand, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132491/
https://www.ncbi.nlm.nih.gov/pubmed/30233139
http://dx.doi.org/10.2147/DDDT.S173671

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132491/
https://www.ncbi.nlm.nih.gov/pubmed/30233139
http://dx.doi.org/10.2147/DDDT.S173671

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