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Possible neurotoxicity of the anesthetic propofol: evidence for the inhibition of complex II of the respiratory chain in area CA3 of rat hippocampal slices

Propofol is the most frequently used intravenous anesthetic for induction and maintenance of anesthesia. Propofol acts first and formost as a GABA(A)-agonist, but effects on other neuronal receptors and voltage-gated ion channels have been described. Besides its direct effect on neurotransmission, p...

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Detalles Bibliográficos
Autores principales:	Berndt, Nikolaus, Rösner, Jörg, Haq, Rizwan ul, Kann, Oliver, Kovács, Richard, Holzhütter, Hermann-Georg, Spies, Claudia, Liotta, Agustin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2018
Materias:	Organ Toxicity and Mechanisms
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132669/ https://www.ncbi.nlm.nih.gov/pubmed/30143847 http://dx.doi.org/10.1007/s00204-018-2295-8

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