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Oprm1 A112G, a single nucleotide polymorphism, alters expression of stress-responsive genes in multiple brain regions in male and female mice

BACKGROUND: OPRM1 A118G, a functional human mu-opioid receptor (MOR) polymorphism, is associated with drug dependence and altered stress responsivity in humans as well as altered MOR signaling. MOR signaling can regulate many cellular processes, including gene expression, and many of the long-term,...

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Detalles Bibliográficos
Autores principales: Collins, Devon, Randesi, Matthew, da Rosa, Joel Correa, Zhang, Yong, Kreek, Mary Jeanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132675/
https://www.ncbi.nlm.nih.gov/pubmed/30027498
http://dx.doi.org/10.1007/s00213-018-4965-x