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The Role of Vitamin D in Brain Health: A Mini Literature Review
Vitamin D is vital for our body as it regulates calcium homeostasis and maintains bone integrity. In this article, we will discuss how vitamin D aids in the function of neuronal and glial tissue and the many health consequences in a person with vitamin D deficiency. Some of the effects of vitamin D...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132681/ https://www.ncbi.nlm.nih.gov/pubmed/30214848 http://dx.doi.org/10.7759/cureus.2960 |
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author | Anjum, Ibrar Jaffery, Syeda S Fayyaz, Muniba Samoo, Zarak Anjum, Sheraz |
author_facet | Anjum, Ibrar Jaffery, Syeda S Fayyaz, Muniba Samoo, Zarak Anjum, Sheraz |
author_sort | Anjum, Ibrar |
collection | PubMed |
description | Vitamin D is vital for our body as it regulates calcium homeostasis and maintains bone integrity. In this article, we will discuss how vitamin D aids in the function of neuronal and glial tissue and the many health consequences in a person with vitamin D deficiency. Some of the effects of vitamin D deficiency that will be discussed include the development of dementia caused by the increase of cerebral soluble and insoluble amyloid-β (Aβ) peptides and a decrease of its anti-inflammatory/antioxidant properties, the link to depression by a reduction of the buffering of increased calcium in the brain, and vitamin D deficiency in expecting mothers linking to the development of autism and schizophrenic-like disorders, hypoxic brain injury, and other mental illnesses. Lastly, we will discuss how vitamin D deficiency is linked to the development of diabetes mellitus, its role in neuronal development and a decrease of microglial inflammatory function leading to increased brain infections. |
format | Online Article Text |
id | pubmed-6132681 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-61326812018-09-13 The Role of Vitamin D in Brain Health: A Mini Literature Review Anjum, Ibrar Jaffery, Syeda S Fayyaz, Muniba Samoo, Zarak Anjum, Sheraz Cureus Endocrinology/Diabetes/Metabolism Vitamin D is vital for our body as it regulates calcium homeostasis and maintains bone integrity. In this article, we will discuss how vitamin D aids in the function of neuronal and glial tissue and the many health consequences in a person with vitamin D deficiency. Some of the effects of vitamin D deficiency that will be discussed include the development of dementia caused by the increase of cerebral soluble and insoluble amyloid-β (Aβ) peptides and a decrease of its anti-inflammatory/antioxidant properties, the link to depression by a reduction of the buffering of increased calcium in the brain, and vitamin D deficiency in expecting mothers linking to the development of autism and schizophrenic-like disorders, hypoxic brain injury, and other mental illnesses. Lastly, we will discuss how vitamin D deficiency is linked to the development of diabetes mellitus, its role in neuronal development and a decrease of microglial inflammatory function leading to increased brain infections. Cureus 2018-07-10 /pmc/articles/PMC6132681/ /pubmed/30214848 http://dx.doi.org/10.7759/cureus.2960 Text en Copyright © 2018, Anjum et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Endocrinology/Diabetes/Metabolism Anjum, Ibrar Jaffery, Syeda S Fayyaz, Muniba Samoo, Zarak Anjum, Sheraz The Role of Vitamin D in Brain Health: A Mini Literature Review |
title | The Role of Vitamin D in Brain Health: A Mini Literature Review |
title_full | The Role of Vitamin D in Brain Health: A Mini Literature Review |
title_fullStr | The Role of Vitamin D in Brain Health: A Mini Literature Review |
title_full_unstemmed | The Role of Vitamin D in Brain Health: A Mini Literature Review |
title_short | The Role of Vitamin D in Brain Health: A Mini Literature Review |
title_sort | role of vitamin d in brain health: a mini literature review |
topic | Endocrinology/Diabetes/Metabolism |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132681/ https://www.ncbi.nlm.nih.gov/pubmed/30214848 http://dx.doi.org/10.7759/cureus.2960 |
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