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3D human liver tissue from pluripotent stem cells displays stable phenotype in vitro and supports compromised liver function in vivo
Liver disease is an escalating global health issue. While liver transplantation is an effective mode of therapy, patient mortality has increased due to the shortage of donor organs. Developing renewable sources of human liver tissue is therefore attractive. Pluripotent stem cell-derived liver tissue...
Autores principales: | Rashidi, Hassan, Luu, Nguyet-Thin, Alwahsh, Salamah M., Ginai, Maaria, Alhaque, Sharmin, Dong, Hua, Tomaz, Rute A., Vernay, Bertrand, Vigneswara, Vasanthy, Hallett, John M., Chandrashekran, Anil, Dhawan, Anil, Vallier, Ludovic, Bradley, Mark, Callanan, Anthony, Forbes, Stuart J., Newsome, Philip N., Hay, David C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132688/ https://www.ncbi.nlm.nih.gov/pubmed/30155720 http://dx.doi.org/10.1007/s00204-018-2280-2 |
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