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Frequency and characteristics of contralateral breast abnormalities following recall at screening mammography

PURPOSE: To determine the frequency and characteristics of contralateral, non-recalled breast abnormalities following recall at screening mammography. METHODS: We included a series of 130,338 screening mammograms performed between 1 January 2014 and 1 January 2016. During the 1-year follow-up, clini...

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Autores principales: Lameijer, Joost R. C., Coolen, Angela MP, Voogd, Adri C., Strobbe, Luc J., Louwman, Marieke W. J., Venderink, Dick, Tjan-Heijnen, Vivian C., Duijm, Lucien E. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132700/
https://www.ncbi.nlm.nih.gov/pubmed/29666991
http://dx.doi.org/10.1007/s00330-018-5370-x
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author Lameijer, Joost R. C.
Coolen, Angela MP
Voogd, Adri C.
Strobbe, Luc J.
Louwman, Marieke W. J.
Venderink, Dick
Tjan-Heijnen, Vivian C.
Duijm, Lucien E. M.
author_facet Lameijer, Joost R. C.
Coolen, Angela MP
Voogd, Adri C.
Strobbe, Luc J.
Louwman, Marieke W. J.
Venderink, Dick
Tjan-Heijnen, Vivian C.
Duijm, Lucien E. M.
author_sort Lameijer, Joost R. C.
collection PubMed
description PURPOSE: To determine the frequency and characteristics of contralateral, non-recalled breast abnormalities following recall at screening mammography. METHODS: We included a series of 130,338 screening mammograms performed between 1 January 2014 and 1 January 2016. During the 1-year follow-up, clinical data were collected for all recalls. Screening outcome was determined for recalled women with or without evaluation of contralateral breast abnormalities. RESULTS: Of 3,995 recalls (recall rate 3.1%), 129 women (3.2%) underwent assessment of a contralateral, non-recalled breast abnormality. Most lesions were detected at clinical mammography and/or breast tomosynthesis (101 women, 78.3%). The biopsy rate was similar for recalled lesions and contralateral, non-recalled lesions, but the positive predictive value of biopsy was higher for recalled lesions (p = 0.01). A comparable proportion of the recalled lesions and contralateral, non-recalled lesions were malignant (p = 0.1). The proportion of ductal carcinoma in situ was similar for both groups, as well as invasive cancer characteristics and type of surgical treatment. CONCLUSIONS: About 3% of recalled women underwent evaluation of contralateral, non-recalled breast lesions. Evaluation of the contralateral breast after recall is important as we found that 15.5% of contralateral, non-recalled lesions were malignant. Contralateral cancers and screen-detected cancers show similar characteristics, stage and surgical treatment. KEY POINTS: • 3% of recalled women underwent evaluation of contralateral, non-recalled lesions • One out of seven contralateral, non-recalled lesions was malignant • A contralateral cancer was diagnosed in 0.5% of recalls • Screen-detected cancers and non-recalled, contralateral cancers showed similar histological characteristics • Tumour stage and surgical treatment were similar for both groups
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spelling pubmed-61327002018-09-13 Frequency and characteristics of contralateral breast abnormalities following recall at screening mammography Lameijer, Joost R. C. Coolen, Angela MP Voogd, Adri C. Strobbe, Luc J. Louwman, Marieke W. J. Venderink, Dick Tjan-Heijnen, Vivian C. Duijm, Lucien E. M. Eur Radiol Breast PURPOSE: To determine the frequency and characteristics of contralateral, non-recalled breast abnormalities following recall at screening mammography. METHODS: We included a series of 130,338 screening mammograms performed between 1 January 2014 and 1 January 2016. During the 1-year follow-up, clinical data were collected for all recalls. Screening outcome was determined for recalled women with or without evaluation of contralateral breast abnormalities. RESULTS: Of 3,995 recalls (recall rate 3.1%), 129 women (3.2%) underwent assessment of a contralateral, non-recalled breast abnormality. Most lesions were detected at clinical mammography and/or breast tomosynthesis (101 women, 78.3%). The biopsy rate was similar for recalled lesions and contralateral, non-recalled lesions, but the positive predictive value of biopsy was higher for recalled lesions (p = 0.01). A comparable proportion of the recalled lesions and contralateral, non-recalled lesions were malignant (p = 0.1). The proportion of ductal carcinoma in situ was similar for both groups, as well as invasive cancer characteristics and type of surgical treatment. CONCLUSIONS: About 3% of recalled women underwent evaluation of contralateral, non-recalled breast lesions. Evaluation of the contralateral breast after recall is important as we found that 15.5% of contralateral, non-recalled lesions were malignant. Contralateral cancers and screen-detected cancers show similar characteristics, stage and surgical treatment. KEY POINTS: • 3% of recalled women underwent evaluation of contralateral, non-recalled lesions • One out of seven contralateral, non-recalled lesions was malignant • A contralateral cancer was diagnosed in 0.5% of recalls • Screen-detected cancers and non-recalled, contralateral cancers showed similar histological characteristics • Tumour stage and surgical treatment were similar for both groups Springer Berlin Heidelberg 2018-04-17 2018 /pmc/articles/PMC6132700/ /pubmed/29666991 http://dx.doi.org/10.1007/s00330-018-5370-x Text en © The Author(s) 2018, corrected publication May 2018 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Breast
Lameijer, Joost R. C.
Coolen, Angela MP
Voogd, Adri C.
Strobbe, Luc J.
Louwman, Marieke W. J.
Venderink, Dick
Tjan-Heijnen, Vivian C.
Duijm, Lucien E. M.
Frequency and characteristics of contralateral breast abnormalities following recall at screening mammography
title Frequency and characteristics of contralateral breast abnormalities following recall at screening mammography
title_full Frequency and characteristics of contralateral breast abnormalities following recall at screening mammography
title_fullStr Frequency and characteristics of contralateral breast abnormalities following recall at screening mammography
title_full_unstemmed Frequency and characteristics of contralateral breast abnormalities following recall at screening mammography
title_short Frequency and characteristics of contralateral breast abnormalities following recall at screening mammography
title_sort frequency and characteristics of contralateral breast abnormalities following recall at screening mammography
topic Breast
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132700/
https://www.ncbi.nlm.nih.gov/pubmed/29666991
http://dx.doi.org/10.1007/s00330-018-5370-x
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