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Backbone NMR assignments of HypF-N under conditions generating toxic and non-toxic oligomers
The HypF protein is involved in the maturation and regulation of hydrogenases. The N-terminal domain of HypF (HypF-N) has served as a key model system to study the pathways of protein amyloid formation and the nature of the toxicity of pre-fibrilar protein oligomers. This domain can aggregate into t...
Autores principales: | Patel, Jayneil R., Xu, Yingqi, Capitini, Claudia, Chiti, Fabrizio, De Simone, Alfonso |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132818/ https://www.ncbi.nlm.nih.gov/pubmed/29786756 http://dx.doi.org/10.1007/s12104-018-9822-7 |
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