Cargando…
Backbone (1)H, (13)C, and (15)N resonance assignments of the ligand binding domain of the human wildtype glucocorticoid receptor and the F602S mutant variant
The glucocorticoid receptor (GR) is a nuclear hormone receptor that regulates key genes controlling development, metabolism, and the immune response. GR agonists are efficacious for treatment of inflammatory, allergic, and immunological disorders. Steroid hormone binding to the ligand-binding domain...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Netherlands
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132842/ https://www.ncbi.nlm.nih.gov/pubmed/29667121 http://dx.doi.org/10.1007/s12104-018-9820-9 |