Patterns and severity of vascular amyloid in Alzheimer’s disease associated with duplications and missense mutations in APP gene, Down syndrome and sporadic Alzheimer’s disease

In this study, we have compared the severity of amyloid plaque formation and cerebral amyloid angiopathy (CAA), and the subtype pattern of CAA pathology itself, between APP genetic causes of AD (APPdup, APP mutations), older individuals with Down syndrome (DS) showing the pathology of Alzheimer’s di...

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Detalles Bibliográficos
Autores principales: Mann, David M. A., Davidson, Yvonne S., Robinson, Andrew C., Allen, Nancy, Hashimoto, Tadafumi, Richardson, Anna, Jones, Matthew, Snowden, Julie S., Pendleton, Neil, Potier, Marie-Claude, Laquerrière, Annie, Prasher, Vee, Iwatsubo, Takeshi, Strydom, Andre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132946/
https://www.ncbi.nlm.nih.gov/pubmed/29770843
http://dx.doi.org/10.1007/s00401-018-1866-3

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