MicroRNA-132 provides neuroprotection for tauopathies via multiple signaling pathways

MicroRNAs (miRNA) regulate fundamental biological processes, including neuronal plasticity, stress response, and survival. Here, we describe a neuroprotective function of miR-132, the miRNA most significantly downregulated in neurons in Alzheimer’s disease. We demonstrate that miR-132 protects prima...

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Detalles Bibliográficos
Autores principales: El Fatimy, Rachid, Li, Shaomin, Chen, Zhicheng, Mushannen, Tasnim, Gongala, Sree, Wei, Zhiyun, Balu, Darrick T., Rabinovsky, Rosalia, Cantlon, Adam, Elkhal, Abdallah, Selkoe, Dennis J., Sonntag, Kai C., Walsh, Dominic M., Krichevsky, Anna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132948/
https://www.ncbi.nlm.nih.gov/pubmed/29982852
http://dx.doi.org/10.1007/s00401-018-1880-5

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