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Calibration and validation of toxicokinetic-toxicodynamic models for three neonicotinoids and some aquatic macroinvertebrates
Exposure patterns in ecotoxicological experiments often do not match the exposure profiles for which a risk assessment needs to be performed. This limitation can be overcome by using toxicokinetic-toxicodynamic (TKTD) models for the prediction of effects under time-variable exposure. For the use of...
Autores principales: | Focks, Andreas, Belgers, Dick, Boerwinkel, Marie-Claire, Buijse, Laura, Roessink, Ivo, Van den Brink, Paul J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132984/ https://www.ncbi.nlm.nih.gov/pubmed/29717389 http://dx.doi.org/10.1007/s10646-018-1940-6 |
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