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Why I use both prospective randomized trials and registry data when choosing the personalized treatment of an AAA patient
Randomized controlled trials (RCTs) have been the core of level 1 data in medical and surgical science for at least the last three decades. However, frequently patient selection is very narrow, anatomic criteria do not match real-world experience, and much of the work is done in selected academic ce...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Medizin
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133084/ https://www.ncbi.nlm.nih.gov/pubmed/30237669 http://dx.doi.org/10.1007/s00772-018-0434-4 |
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author | Shah, M. D. Edeiken, S. Darling III, R. C. |
author_facet | Shah, M. D. Edeiken, S. Darling III, R. C. |
author_sort | Shah, M. D. |
collection | PubMed |
description | Randomized controlled trials (RCTs) have been the core of level 1 data in medical and surgical science for at least the last three decades. However, frequently patient selection is very narrow, anatomic criteria do not match real-world experience, and much of the work is done in selected academic centers. We use RCTs to help explain the rational for intervention and then rely on longitudinal registries and single center data to give the patients a real-world expectation concerning outcomes and complications in our hands. |
format | Online Article Text |
id | pubmed-6133084 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Springer Medizin |
record_format | MEDLINE/PubMed |
spelling | pubmed-61330842018-09-18 Why I use both prospective randomized trials and registry data when choosing the personalized treatment of an AAA patient Shah, M. D. Edeiken, S. Darling III, R. C. Gefasschirurgie Leitthema Randomized controlled trials (RCTs) have been the core of level 1 data in medical and surgical science for at least the last three decades. However, frequently patient selection is very narrow, anatomic criteria do not match real-world experience, and much of the work is done in selected academic centers. We use RCTs to help explain the rational for intervention and then rely on longitudinal registries and single center data to give the patients a real-world expectation concerning outcomes and complications in our hands. Springer Medizin 2018-08-09 2018 /pmc/articles/PMC6133084/ /pubmed/30237669 http://dx.doi.org/10.1007/s00772-018-0434-4 Text en © The Author(s) 2018 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Leitthema Shah, M. D. Edeiken, S. Darling III, R. C. Why I use both prospective randomized trials and registry data when choosing the personalized treatment of an AAA patient |
title | Why I use both prospective randomized trials and registry data when choosing the personalized treatment of an AAA patient |
title_full | Why I use both prospective randomized trials and registry data when choosing the personalized treatment of an AAA patient |
title_fullStr | Why I use both prospective randomized trials and registry data when choosing the personalized treatment of an AAA patient |
title_full_unstemmed | Why I use both prospective randomized trials and registry data when choosing the personalized treatment of an AAA patient |
title_short | Why I use both prospective randomized trials and registry data when choosing the personalized treatment of an AAA patient |
title_sort | why i use both prospective randomized trials and registry data when choosing the personalized treatment of an aaa patient |
topic | Leitthema |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133084/ https://www.ncbi.nlm.nih.gov/pubmed/30237669 http://dx.doi.org/10.1007/s00772-018-0434-4 |
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