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Why I use both prospective randomized trials and registry data when choosing the personalized treatment of an AAA patient

Randomized controlled trials (RCTs) have been the core of level 1 data in medical and surgical science for at least the last three decades. However, frequently patient selection is very narrow, anatomic criteria do not match real-world experience, and much of the work is done in selected academic ce...

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Detalles Bibliográficos
Autores principales: Shah, M. D., Edeiken, S., Darling III, R. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Medizin 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133084/
https://www.ncbi.nlm.nih.gov/pubmed/30237669
http://dx.doi.org/10.1007/s00772-018-0434-4
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author Shah, M. D.
Edeiken, S.
Darling III, R. C.
author_facet Shah, M. D.
Edeiken, S.
Darling III, R. C.
author_sort Shah, M. D.
collection PubMed
description Randomized controlled trials (RCTs) have been the core of level 1 data in medical and surgical science for at least the last three decades. However, frequently patient selection is very narrow, anatomic criteria do not match real-world experience, and much of the work is done in selected academic centers. We use RCTs to help explain the rational for intervention and then rely on longitudinal registries and single center data to give the patients a real-world expectation concerning outcomes and complications in our hands.
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spelling pubmed-61330842018-09-18 Why I use both prospective randomized trials and registry data when choosing the personalized treatment of an AAA patient Shah, M. D. Edeiken, S. Darling III, R. C. Gefasschirurgie Leitthema Randomized controlled trials (RCTs) have been the core of level 1 data in medical and surgical science for at least the last three decades. However, frequently patient selection is very narrow, anatomic criteria do not match real-world experience, and much of the work is done in selected academic centers. We use RCTs to help explain the rational for intervention and then rely on longitudinal registries and single center data to give the patients a real-world expectation concerning outcomes and complications in our hands. Springer Medizin 2018-08-09 2018 /pmc/articles/PMC6133084/ /pubmed/30237669 http://dx.doi.org/10.1007/s00772-018-0434-4 Text en © The Author(s) 2018 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Leitthema
Shah, M. D.
Edeiken, S.
Darling III, R. C.
Why I use both prospective randomized trials and registry data when choosing the personalized treatment of an AAA patient
title Why I use both prospective randomized trials and registry data when choosing the personalized treatment of an AAA patient
title_full Why I use both prospective randomized trials and registry data when choosing the personalized treatment of an AAA patient
title_fullStr Why I use both prospective randomized trials and registry data when choosing the personalized treatment of an AAA patient
title_full_unstemmed Why I use both prospective randomized trials and registry data when choosing the personalized treatment of an AAA patient
title_short Why I use both prospective randomized trials and registry data when choosing the personalized treatment of an AAA patient
title_sort why i use both prospective randomized trials and registry data when choosing the personalized treatment of an aaa patient
topic Leitthema
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133084/
https://www.ncbi.nlm.nih.gov/pubmed/30237669
http://dx.doi.org/10.1007/s00772-018-0434-4
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