Autologous Mesenchymal Stromal Cells Prevent Transfusion-elicited Sensitization and Upregulate Transitional and Regulatory B Cells

BACKGROUND: We hypothesized that immunomodulatory properties of mesenchymal stromal cells (MSC) may be considered for desensitization. METHODS: Autologous or allogeneic bone marrow derived MSC were infused via tail vein at 0.5 M (0.5 × 10(6)), 1 M, or 2 M cells/dose on days −2, 3, 6, 9, 12 (preventi...

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Detalles Bibliográficos
Autores principales: Zhang, Zijian, Wilson, Nancy A., Chinnadurai, Raghavan, Panzer, Sarah E., Redfield, Robert R., Reese, Shannon R., Galipeau, Jacques, Djamali, Arjang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Kidney Transplantation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133404/
https://www.ncbi.nlm.nih.gov/pubmed/30234156
http://dx.doi.org/10.1097/TXD.0000000000000827

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133404/
https://www.ncbi.nlm.nih.gov/pubmed/30234156
http://dx.doi.org/10.1097/TXD.0000000000000827

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