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CSF biomarkers of neuroinflammation and cerebrovascular dysfunction in early Alzheimer disease

OBJECTIVE: To measure CSF levels of biomarkers reflecting microglia and astrocytes activation, neuroinflammation, and cerebrovascular changes and study their associations with the core biomarkers of Alzheimer disease (AD) pathology (β-amyloid [Aβ] and tau), structural imaging correlates, and clinica...

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Detalles Bibliográficos
Autores principales: Janelidze, Shorena, Mattsson, Niklas, Stomrud, Erik, Lindberg, Olof, Palmqvist, Sebastian, Zetterberg, Henrik, Blennow, Kaj, Hansson, Oskar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133624/
https://www.ncbi.nlm.nih.gov/pubmed/30054439
http://dx.doi.org/10.1212/WNL.0000000000006082