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Ceramide synthase-6 confers resistance to chemotherapy by binding to CD95/Fas in T-cell acute lymphoblastic leukemia

Ceramide synthases (CERS) produce ceramides which are key intermediators in the biosynthesis of complex sphingolipids and play an important role in cell proliferation, differentiation, apoptosis and senescence. CERS6 is an isoform of ceramide synthases known to generate ceramides with C16 acyl chain...

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Detalles Bibliográficos
Autores principales:	Verlekar, Dattesh, Wei, Sung-Jen, Cho, Hwangeui, Yang, Shengping, Kang, Min H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133972/ https://www.ncbi.nlm.nih.gov/pubmed/30206207 http://dx.doi.org/10.1038/s41419-018-0964-4

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