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Effect of Anti-IL17 Antibody Treatment Alone and in Combination With Rho-Kinase Inhibitor in a Murine Model of Asthma

Background: Interleukin-17 (IL-17) and Rho-kinase (ROCK) play an important role in regulating the expression of inflammatory mediators, immune cell recruitment, hyper-responsiveness, tissue remodeling, and oxidative stress. Modulation of IL-17 and ROCK proteins may represent a promising approach for...

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Detalles Bibliográficos
Autores principales:	dos Santos, Tabata M., Righetti, Renato F., Camargo, Leandro do N., Saraiva-Romanholo, Beatriz M., Aristoteles, Luciana R. C. R. B., de Souza, Flávia C. R., Fukuzaki, Silvia, Alonso-Vale, Maria I. C., Cruz, Maysa M., Prado, Carla M., Leick, Edna A., Martins, Milton A., Tibério, Iolanda F. L. C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134017/ https://www.ncbi.nlm.nih.gov/pubmed/30233389 http://dx.doi.org/10.3389/fphys.2018.01183

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