Increased Binding of Specificity Protein 1 to the IL21R Promoter in B Cells Results in Enhanced B Cell Responses in Rheumatoid Arthritis

B cells are implicated in rheumatoid arthritis (RA) based on the presence of autoantibodies and the therapeutic response to B cell depletion. IL-21 has a significant role in B cell development and function. Here we assess B cell responses to IL-21 and the mechanisms responsible for altered IL-21R ex...

Descripción completa

Detalles Bibliográficos
Autores principales: Dam, Elizabeth M., Maier, Alison C., Hocking, Anne M., Carlin, Jeffrey, Ng, Bernard, Buckner, Jane H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134023/
https://www.ncbi.nlm.nih.gov/pubmed/30233580
http://dx.doi.org/10.3389/fimmu.2018.01978

Ejemplares similares

Ejemplares similares