Cargando…

Localization of RNAi Machinery to Axonal Branch Points and Growth Cones Is Facilitated by Mitochondria and Is Disrupted in ALS

Local protein synthesis in neuronal axons plays an important role in essential spatiotemporal signaling processes; however, the molecular basis for the post-transcriptional regulation controlling this process in axons is still not fully understood. Here we studied the axonal mechanisms underlying th...

Descripción completa

Detalles Bibliográficos
Autores principales: Gershoni-Emek, Noga, Altman, Topaz, Ionescu, Ariel, Costa, Christopher J., Gradus-Pery, Tal, Willis, Dianna E., Perlson, Eran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134038/
https://www.ncbi.nlm.nih.gov/pubmed/30233312
http://dx.doi.org/10.3389/fnmol.2018.00311