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An Ad/MVA vectored Theileria parva antigen induces schizont-specific CD8(+) central memory T cells and confers partial protection against a lethal challenge
The parasite Theileria parva is the causative agent of East Coast fever (ECF), one of the most serious cattle diseases in sub-Saharan Africa, and directly impacts smallholder farmers’ livelihoods. There is an efficient live-parasite vaccine, but issues with transmission of vaccine strains, need of a...
Autores principales: | Svitek, Nicholas, Saya, Rosemary, Awino, Elias, Munyao, Stephen, Muriuki, Robert, Njoroge, Thomas, Pellé, Roger, Ndiwa, Nicholas, Poole, Jane, Gilbert, Sarah, Nene, Vishvanath, Steinaa, Lucilla |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134044/ https://www.ncbi.nlm.nih.gov/pubmed/30245859 http://dx.doi.org/10.1038/s41541-018-0073-5 |
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