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Serum IgG2 levels are specifically associated with whole-body insulin-mediated glucose disposal in non-diabetic offspring of type 2 diabetic individuals: a cross-sectional study
Preclinical studies suggested that IgG2c isotype may specifically impair skeletal muscle insulin sensitivity in mice. In this study we investigated the association between serum levels of the four IgG subclasses and insulin sensitivity in non-diabetic individuals. Total IgG, IgG1, IgG2, IgG3 and IgG...
Autores principales: | Fiorentino, Teresa Vanessa, Succurro, Elena, Arturi, Franco, Giancotti, Aida, Peronace, Cinzia, Quirino, Angela, Sesti, Franz, Andreozzi, Francesco, Hribal, Marta Letizia, Perticone, Francesco, Focà, Alfredo, Sesti, Giorgio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134058/ https://www.ncbi.nlm.nih.gov/pubmed/30206293 http://dx.doi.org/10.1038/s41598-018-32108-8 |
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