Targeting a phospho-STAT3-miRNAs pathway improves vesicular hepatic steatosis in an in vitro and in vivo model

Non-alcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver disease. Although genetic predisposition and epigenetic factors contribute to the development of NAFLD, our understanding of the molecular mechanism involved in the pathogenesis of the disease is still emerging. Here we in...

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Detalles Bibliográficos
Autores principales: Belloni, Laura, Di Cocco, Silvia, Guerrieri, Francesca, Nunn, Abigail D. G., Piconese, Silvia, Salerno, Debora, Testoni, Barbara, Pulito, Claudio, Mori, Federica, Pallocca, Matteo, Sacconi, Andrea, Vivoli, Elisa, Marra, Fabio, Strano, Sabrina, Blandino, Giovanni, Levrero, Massimo, Pediconi, Natalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134080/
https://www.ncbi.nlm.nih.gov/pubmed/30206377
http://dx.doi.org/10.1038/s41598-018-31835-2

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