Exome-wide analysis identifies three low-frequency missense variants associated with pancreatic cancer risk in Chinese populations

Germline coding variants have not been systematically investigated for pancreatic ductal adenocarcinoma (PDAC). Here we report an exome-wide investigation using the Illumina Human Exome Beadchip with 943 PDAC cases and 3908 controls in the Chinese population, followed by two independent replicate sa...

Descripción completa

Detalles Bibliográficos
Autores principales: Chang, Jiang, Tian, Jianbo, Zhu, Ying, Zhong, Rong, Zhai, Kan, Li, Jiaoyuan, Ke, Juntao, Han, QiangQiang, Lou, Jiao, Chen, Wei, Zhu, Beibei, Shen, Na, Zhang, Yi, Gong, Yajie, Yang, Yang, Zou, Danyi, Peng, Xiating, Zhang, Zhi, Zhang, Xuemei, Huang, Kun, Yang, Ming, Wang, Li, Wu, Chen, Lin, Dongxin, Miao, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134090/
https://www.ncbi.nlm.nih.gov/pubmed/30206226
http://dx.doi.org/10.1038/s41467-018-06136-x

Ejemplares similares

Ejemplares similares