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Tumor Necrosis Factor Alpha Induces Reactivation of Human Cytomegalovirus Independently of Myeloid Cell Differentiation following Posttranscriptional Establishment of Latency

We used the Kasumi-3 model to study human cytomegalovirus (HCMV) latency and reactivation in myeloid progenitor cells. Kasumi-3 cells were infected with HCMV strain TB40/Ewt-GFP, flow sorted for green fluorescent protein-positive (GFP(+)) cells, and cultured for various times to monitor establishmen...

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Detalles Bibliográficos
Autores principales: Forte, Eleonora, Swaminathan, Suchitra, Schroeder, Mark W., Kim, Jeong Yeon, Terhune, Scott S., Hummel, Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134100/
https://www.ncbi.nlm.nih.gov/pubmed/30206173
http://dx.doi.org/10.1128/mBio.01560-18