Ectopic hTERT expression facilitates reprograming of fibroblasts derived from patients with Werner syndrome as a WS cellular model

The induced pluripotent stem cell (iPSC) technology has provided a unique opportunity to develop disease-specific models and personalized treatment for genetic disorders, and is well suitable for the study of Werner syndrome (WS), an autosomal recessive disease with adult onset of premature aging ca...

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Detalles Bibliográficos
Autores principales: Wang, Shuyan, Liu, Zhongfeng, Ye, Yanxia, Li, Bingnan, Liu, Tiantian, Zhang, Weiqi, Liu, Guang-Hui, Zhang, Y. Alex, Qu, Jing, Xu, Dawei, Chen, Zhiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134116/
https://www.ncbi.nlm.nih.gov/pubmed/30206203
http://dx.doi.org/10.1038/s41419-018-0948-4

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