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Evidence for Regulation of Hemoglobin Metabolism and Intracellular Ionic Flux by the Plasmodium falciparum Chloroquine Resistance Transporter

Plasmodium falciparum multidrug resistance constitutes a major obstacle to the global malaria elimination campaign. Specific mutations in the Plasmodium falciparum chloroquine resistance transporter (PfCRT) mediate resistance to the 4-aminoquinoline drug chloroquine and impact parasite susceptibilit...

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Detalles Bibliográficos
Autores principales: Lee, Andrew H., Dhingra, Satish K., Lewis, Ian A., Singh, Maneesh K., Siriwardana, Amila, Dalal, Seema, Rubiano, Kelly, Klein, Matthias S., Baska, Katelynn S., Krishna, Sanjeev, Klemba, Michael, Roepe, Paul D., Llinás, Manuel, Garcia, Celia R. S., Fidock, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134138/
https://www.ncbi.nlm.nih.gov/pubmed/30206341
http://dx.doi.org/10.1038/s41598-018-31715-9