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Evidence for Regulation of Hemoglobin Metabolism and Intracellular Ionic Flux by the Plasmodium falciparum Chloroquine Resistance Transporter
Plasmodium falciparum multidrug resistance constitutes a major obstacle to the global malaria elimination campaign. Specific mutations in the Plasmodium falciparum chloroquine resistance transporter (PfCRT) mediate resistance to the 4-aminoquinoline drug chloroquine and impact parasite susceptibilit...
Autores principales: | Lee, Andrew H., Dhingra, Satish K., Lewis, Ian A., Singh, Maneesh K., Siriwardana, Amila, Dalal, Seema, Rubiano, Kelly, Klein, Matthias S., Baska, Katelynn S., Krishna, Sanjeev, Klemba, Michael, Roepe, Paul D., Llinás, Manuel, Garcia, Celia R. S., Fidock, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134138/ https://www.ncbi.nlm.nih.gov/pubmed/30206341 http://dx.doi.org/10.1038/s41598-018-31715-9 |
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