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Selenium supplementation of lung epithelial cells enhances nuclear factor E2-related factor 2 (Nrf2) activation following thioredoxin reductase inhibition

The trace element selenium (Se) contributes to redox signaling, antioxidant defense, and immune responses in critically ill neonatal and adult patients. Se is required for the synthesis and function of selenoenzymes including thioredoxin (Trx) reductase-1 (TXNRD1) and glutathione peroxidases (GPx)....

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Detalles Bibliográficos
Autores principales: Tindell, Rachael, Wall, Stephanie B., Li, Qian, Li, Rui, Dunigan, Katelyn, Wood, Rachael, Tipple, Trent E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134185/
https://www.ncbi.nlm.nih.gov/pubmed/30212802
http://dx.doi.org/10.1016/j.redox.2018.07.020

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