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Selenium supplementation of lung epithelial cells enhances nuclear factor E2-related factor 2 (Nrf2) activation following thioredoxin reductase inhibition
The trace element selenium (Se) contributes to redox signaling, antioxidant defense, and immune responses in critically ill neonatal and adult patients. Se is required for the synthesis and function of selenoenzymes including thioredoxin (Trx) reductase-1 (TXNRD1) and glutathione peroxidases (GPx)....
Autores principales: | Tindell, Rachael, Wall, Stephanie B., Li, Qian, Li, Rui, Dunigan, Katelyn, Wood, Rachael, Tipple, Trent E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134185/ https://www.ncbi.nlm.nih.gov/pubmed/30212802 http://dx.doi.org/10.1016/j.redox.2018.07.020 |
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