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Optimization of the Linker Length of Mannose-Cholesterol Conjugates for Enhanced mRNA Delivery to Dendritic Cells by Liposomes

Liposomes (LPs) as commonly used mRNA delivery systems remain to be rationally designed and optimized to ameliorate the antigen expression of mRNA vaccine in dendritic cells (DCs). In this study, we synthesized mannose-cholesterol conjugates (MP(n)-CHs) by click reaction using different PEG units (P...

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Detalles Bibliográficos
Autores principales:	Wang, Fazhan, Xiao, Wen, Elbahnasawy, Mostafa A., Bao, Xingting, Zheng, Qian, Gong, Linhui, Zhou, Yang, Yang, Shuping, Fang, Aiping, Farag, Mohamed M. S., Wu, Jinhui, Song, Xiangrong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134263/ https://www.ncbi.nlm.nih.gov/pubmed/30233368 http://dx.doi.org/10.3389/fphar.2018.00980

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