Unique interstitial miRNA signature drives fibrosis in a murine model of autosomal dominant polycystic kidney disease

AIM: To delineate changes in miRNA expression localized to the peri-cystic local microenvironment (PLM) in an orthologous mouse model of autosomal dominant polycystic kidney disease (ADPKD) (mcwPkd1((nl/nl))). METHODS: We profiled miRNA expression in the whole kidney and laser captured microdissecti...

Descripción completa

Detalles Bibliográficos
Autores principales: Patil, Ameya, Jr, William E Sweeney, Pan, Cynthia G, Avner, Ellis D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2018
Materias:
Basic Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134266/
https://www.ncbi.nlm.nih.gov/pubmed/30211029
http://dx.doi.org/10.5527/wjn.v7.i5.108

Ejemplares similares

Ejemplares similares