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Key Role of the Membrane Trafficking of Nav1.5 Channel Protein in Antidepressant-Induced Brugada Syndrome
Anti-depressant treatment has been found to be associated with the development of Brugada syndrome (BrS) through poorly defined mechanisms. Herein, this study aimed to explore the molecular basis for amitriptyline-induced BrS. The effects of long-term treatments of amitriptyline on Nav1.5 were inves...
Autores principales: | Chen, Xi, Zhu, Chao, Zhou, Hao, Zhang, Yu, Cai, Zhongqi, Wu, Honglin, Ren, Xiaomeng, Gao, Lei, Zhang, Jiancheng, Li, Yang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134322/ https://www.ncbi.nlm.nih.gov/pubmed/30233406 http://dx.doi.org/10.3389/fphys.2018.01230 |
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