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Osteomalacia, renal Fanconi syndrome, and bone tumor
We herein report two cases of Fanconi syndrome with refractory hypophosphatemic osteomalacia that was difficult to correct by phosphorus replacement therapy. The pathological result was a bony giant cell tumor and osteosarcoma, respectively. Interestingly, after resection of the tumors, the patient...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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SAGE Publications
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134638/ https://www.ncbi.nlm.nih.gov/pubmed/29614898 http://dx.doi.org/10.1177/0300060518763708 |
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author | Gou, Manting Ma, Zhongshu |
author_facet | Gou, Manting Ma, Zhongshu |
author_sort | Gou, Manting |
collection | PubMed |
description | We herein report two cases of Fanconi syndrome with refractory hypophosphatemic osteomalacia that was difficult to correct by phosphorus replacement therapy. The pathological result was a bony giant cell tumor and osteosarcoma, respectively. Interestingly, after resection of the tumors, the patient with osteosarcoma recovered completely but the patient with the bony giant cell tumor had a relapse. Although she underwent nine operations, her symptoms and laboratory tests did not improve. These findings indicate that Fanconi syndrome can result from a bone tumor. |
format | Online Article Text |
id | pubmed-6134638 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-61346382018-09-13 Osteomalacia, renal Fanconi syndrome, and bone tumor Gou, Manting Ma, Zhongshu J Int Med Res Case Reports We herein report two cases of Fanconi syndrome with refractory hypophosphatemic osteomalacia that was difficult to correct by phosphorus replacement therapy. The pathological result was a bony giant cell tumor and osteosarcoma, respectively. Interestingly, after resection of the tumors, the patient with osteosarcoma recovered completely but the patient with the bony giant cell tumor had a relapse. Although she underwent nine operations, her symptoms and laboratory tests did not improve. These findings indicate that Fanconi syndrome can result from a bone tumor. SAGE Publications 2018-04-03 2018-08 /pmc/articles/PMC6134638/ /pubmed/29614898 http://dx.doi.org/10.1177/0300060518763708 Text en © The Author(s) 2018 http://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Case Reports Gou, Manting Ma, Zhongshu Osteomalacia, renal Fanconi syndrome, and bone tumor |
title | Osteomalacia, renal Fanconi syndrome, and bone tumor |
title_full | Osteomalacia, renal Fanconi syndrome, and bone tumor |
title_fullStr | Osteomalacia, renal Fanconi syndrome, and bone tumor |
title_full_unstemmed | Osteomalacia, renal Fanconi syndrome, and bone tumor |
title_short | Osteomalacia, renal Fanconi syndrome, and bone tumor |
title_sort | osteomalacia, renal fanconi syndrome, and bone tumor |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134638/ https://www.ncbi.nlm.nih.gov/pubmed/29614898 http://dx.doi.org/10.1177/0300060518763708 |
work_keys_str_mv | AT goumanting osteomalaciarenalfanconisyndromeandbonetumor AT mazhongshu osteomalaciarenalfanconisyndromeandbonetumor |