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Osteomalacia, renal Fanconi syndrome, and bone tumor

We herein report two cases of Fanconi syndrome with refractory hypophosphatemic osteomalacia that was difficult to correct by phosphorus replacement therapy. The pathological result was a bony giant cell tumor and osteosarcoma, respectively. Interestingly, after resection of the tumors, the patient...

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Detalles Bibliográficos
Autores principales: Gou, Manting, Ma, Zhongshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134638/
https://www.ncbi.nlm.nih.gov/pubmed/29614898
http://dx.doi.org/10.1177/0300060518763708
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author Gou, Manting
Ma, Zhongshu
author_facet Gou, Manting
Ma, Zhongshu
author_sort Gou, Manting
collection PubMed
description We herein report two cases of Fanconi syndrome with refractory hypophosphatemic osteomalacia that was difficult to correct by phosphorus replacement therapy. The pathological result was a bony giant cell tumor and osteosarcoma, respectively. Interestingly, after resection of the tumors, the patient with osteosarcoma recovered completely but the patient with the bony giant cell tumor had a relapse. Although she underwent nine operations, her symptoms and laboratory tests did not improve. These findings indicate that Fanconi syndrome can result from a bone tumor.
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spelling pubmed-61346382018-09-13 Osteomalacia, renal Fanconi syndrome, and bone tumor Gou, Manting Ma, Zhongshu J Int Med Res Case Reports We herein report two cases of Fanconi syndrome with refractory hypophosphatemic osteomalacia that was difficult to correct by phosphorus replacement therapy. The pathological result was a bony giant cell tumor and osteosarcoma, respectively. Interestingly, after resection of the tumors, the patient with osteosarcoma recovered completely but the patient with the bony giant cell tumor had a relapse. Although she underwent nine operations, her symptoms and laboratory tests did not improve. These findings indicate that Fanconi syndrome can result from a bone tumor. SAGE Publications 2018-04-03 2018-08 /pmc/articles/PMC6134638/ /pubmed/29614898 http://dx.doi.org/10.1177/0300060518763708 Text en © The Author(s) 2018 http://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Reports
Gou, Manting
Ma, Zhongshu
Osteomalacia, renal Fanconi syndrome, and bone tumor
title Osteomalacia, renal Fanconi syndrome, and bone tumor
title_full Osteomalacia, renal Fanconi syndrome, and bone tumor
title_fullStr Osteomalacia, renal Fanconi syndrome, and bone tumor
title_full_unstemmed Osteomalacia, renal Fanconi syndrome, and bone tumor
title_short Osteomalacia, renal Fanconi syndrome, and bone tumor
title_sort osteomalacia, renal fanconi syndrome, and bone tumor
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134638/
https://www.ncbi.nlm.nih.gov/pubmed/29614898
http://dx.doi.org/10.1177/0300060518763708
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